The immune reaction to EIAV may also affect blood vessels and vital organs. Hemorrhage, thrombosis, or blockage of blood vessels, and edema can occur, and are secondary to immune-mediated vasculitis, or inflammation of the vessels. Vasculitis and lymphocyte accumulation in the meninges, or lining tissues of the brain and spinal cord, occasionally result in ataxia, or incoordination of movement. Accumulations of lymphocytes and macrophages in the liver can result in hepatomegaly, or liver enlargement, fatty degeneration, and hepatic cell death, while immune complex deposition can result in glomerulitis, or inflammation of specialized structures in the kidney.