We have investigated the fiber transmission performance of the single-sideband optical orthogonal frequency division multiplexing (SSB-OOFDM) signal with reduced guard band (GB) received by the beat interference cancellation receiver based on balanced detection (ICRBD). The simulation results show that the error vector magnitude (EVM) of the 40 Gb/s 16-QAM SSB-OOFDM with 2 GHz GB remains below the forward error correction (FEC) limit even after 5×100 km standard single-mode fiber (SSMF) transmission. The link has stable tolerance of both the laser linewidth and the linear channel imperfections.