• Blood in the urine. With cystitis, you may have blood cells in your urine that can be seen only with a microscope (microscopic hematuria) and that usually resolves with treatment. If blood cells remain after treatment, your doctor may recommend a specialist to determine the cause. Blood in the urine that you can see (gross hematuria) is rare with typical, bacterial cystitis, but this sign is not uncommon with chemotherapy- or radiation-induced cystitis.