The ergonomics design of transport category airplane cockpit is of great importance to the efficiency of flight crew operation and has a major impact on the flight safety. In this work, the ergonomics design elements in the cockpit are analyzed. The elements are collected from airworthiness regulations, industry standards, features of new generation airplane cockpit and the interaction process analysis results. Using hierarchical cluster approach, the ergonomics design elements are clustered, and the ergonomics design elements for transport category airplane cockpit are determined. The cockpit design process is presented on the basis of axiomatic design theory and a framework for ergonomics design of transport category airplane cockpit.