Assessment of MCP on glucose tolerance
After overnight fasting, the hypoglycemic effects of MCP in nor-mal healthy and alloxan-induced diabetic mice were assessed by the improvement of glucose tolerance. Fasting blood glucose was taken from over-night fasted mice
The mice (n = 10 per group)were divided into six groups. Group a (normal control), normalmice treated with vehicle (distilled water) alone; Group b (diabeticcontrol), diabetic mice treated with vehicle alone; Group c (pos-itive control), diabetic mice treated with Xiaoke pill (200 mg/kgbody weight); Group d (MCP-L), diabetic mice treated with MCP(100 mg/kg body weight); Group e (MCP-M), diabetic mice treatedwith MCP (200 mg/kg body weight); Group f (MCP-H), diabetic mic etreated with MCP (300 mg/kg body weight).
The mice of all the groups were given glucose (as aqueous solution, 2 g/kg, body weight) after 90 min of MCP and vehicle administration. Blood samples were collected for glucose levelsetimation just prior to the administration of the glucose (0 min)and 30, 60, and 120 min after the glucose loading.
Assessment of MCP on glucose toleranceAfter overnight fasting, the hypoglycemic effects of MCP in nor-mal healthy and alloxan-induced diabetic mice were assessed by the improvement of glucose tolerance. Fasting blood glucose was taken from over-night fasted mice The mice (n = 10 per group)were divided into six groups. Group a (normal control), normalmice treated with vehicle (distilled water) alone; Group b (diabeticcontrol), diabetic mice treated with vehicle alone; Group c (pos-itive control), diabetic mice treated with Xiaoke pill (200 mg/kgbody weight); Group d (MCP-L), diabetic mice treated with MCP(100 mg/kg body weight); Group e (MCP-M), diabetic mice treatedwith MCP (200 mg/kg body weight); Group f (MCP-H), diabetic mic etreated with MCP (300 mg/kg body weight).The mice of all the groups were given glucose (as aqueous solution, 2 g/kg, body weight) after 90 min of MCP and vehicle administration. Blood samples were collected for glucose levelsetimation just prior to the administration of the glucose (0 min)and 30, 60, and 120 min after the glucose loading.
การแปล กรุณารอสักครู่..
