Fig. 3.
The pyruvate carboxylase inhibitor phenylacetic acid (PAA) reduces both glucose-oxidation and secretion of citrate from human myotubes at a high glucose concentration. Human myotubes were exposed to 5 and 15.0 mmol glucose with/without 10.0 mmol/l PAA and glucose-oxidation and citrate concentration in media measured. Data are shown as means ± SEM. N = 8. ∗p < 0.05 vs. previously lower glucose concentration.