Seventy-five overweight or obese men (BMI >25 kg/m 2 ), aged 30 to 55 y,
were invited to participate in the study (43 completed the study and 32 dropped
out for personal reasons) from the community served by the Department of
Medical Sciences of The University of Guanajuato (Le ? on, M ? exico) using adver-
tisement in local newspapers and on the radio. Interested individuals were
screened by personal interview with a member of the research team. Participants
were required to be sedentary or relatively inactive; involved in less than three
sessions of 30 min each per week of physical activity; nonsmokers; and free of
known chronic diseases including diabetes, renal, or cardiovascular disease.
Participants were randomly assigned to one of three groups: a low AGE diet
(group 1), an exercise with habitual food intake (group 2), or an exercise plus low
AGE diet group (group 3). Randomization was done according to aleatory
numbers generated by computer and were kept in consecutively numbered en-
velopes opened at the moment of participant enrollment into the study. All
participants signed an informed consent approved by the Institutional Review
Board at the Department of Medical Sciences. Universidad de Guanajuato, Gua-
najuato, M ? exico.