Depression Status Depression status has been shown to moderate the efficacy of positive psychology interventions, such that depressed individuals generally experience more improvement in well-being and greater reductions in depressive symptoms relative to nondepressed ones (Sin & Lyubomirsky, 2009). However, this finding is confounded with treatment format; studies that use clinically depressed participants tend to treat them with individual or group therapies (which offer attention and guidance from a clinician) rather than self-administered interventions. To our knowledge, studies have not compared the efficacy of self-administered positive interventions in depressed versus non-depressed samples