[3]. A daily dose of 2 grams of Curcuma domestic extract was found to provide pain relief that was equivalent to ibuprofen for the relief of pain associated with osteoarthritis of the knee[3]. Commercial capsules of curcumin contain piperine, a compound found in pepper which aids absorption of curcumin into the blood stream. Curcumin might be potentially useful in some kidney diseases by preventing renal inflammation.[ 12]