Recently, G. mangostana fruit extract is popularly used as a food supplement while the fruit rind extract has been used in herbal medicines, herbal cosmetics and pharmaceutical products for treatment of acne.
Due to wide therapeutic uses of bioactive components and variation of their contents at different stages of mangosteen fruits, this work was aimed to determine and compare the contents of bioactive components i.e. total phenolic compounds, total tannins, total flavonoids and α-mangostin in young and mature fruit rind extracts from G. mangostana. More over, free radical scavenging and antibacterial activities against P. acnes and S. epidermidis, which are bacteria involved in acne development, of these extracts were also determined and compared.