The study was conducted in December 2012, in the facilities ofthe UMR1213 Research Unit and the UE1354 Experimental
Unit of INRA Auvergne-Rhône-Alpes in Central France (45◦42 N, 03◦30 E). All the procedures were conducted in accordance
with the European Union Directive No. 609/1986 and French Guidelines for the use of experimental animals and compliant
with animal welfare and good practice