magnesium participates in more than 300 types of enzyme-mediated reaction in the body, including those in DNA and protein synthesis. In the mitochondria, magnesium is essential for the production of ATP via the electron transport chain, Since ATP is the universal energy source for all cell, an absence of magnesium would quickly half cellular activity . In the glycolysis pathway alone, seven key enzyme require magnesium. Magnesium also participates in muscle contraction and blood clotting.