Human albumin, commonly cited for its volume
expansion and osmotic and oncotic pressures, is poorly
studied for its bioprotective effect of coating synthetic
surfaces.13–16 With between 375 μg/ml prime and 1 to 10
mg/m2 of albumin being required to form a monolayer
on a synthetic surface,13,19 only a small amount of albumin
is required to offer bioprotection in the extracorporeal
circuit.