The
structures of these constituents were determined by extensive NMR and mass spectroscopy. Compound 1 was subjected to diverse in vitro bioassays, including cytotoxicity, immunomodulatory, antiglycation, antioxidant and enzyme inhibition assays. To the best of our knowledge, this is the first report of isolation of an isohopane triterpene from the genus Carissa as well as the first
example of a cytotoxic isohopane.