For cases of uncomplicated cholecystitis, outpatient treatment may be appropriate. The following medications may be useful in this setting:
Levofloxacin and metronidazole for prophylactic antibiotic coverage against the most common organisms
Antiemetics (eg, promethazine or prochlorperazine) to control nausea and prevent fluid and electrolyte disorders
Analgesics (eg, oxycodone/acetaminophen)