In the ecological analysis, the nationwide average mortality was
lower than 1 per 100,000 persons in mainland China during the
first decade of the 21st century. The sepsis mortality in small and
medium-sized cities and rural areas declined significantly over
time, but there was a slight increase in the mortality in major cities.
The mortality of the elderly with sepsis declined, but that of
neonates with sepsis increased dramatically, especially among
male neonates. In the epidemiological study review, the overall
positivity of the blood cultures were 17.0%, 13.3% and 10.6% among
neonatal, pediatric and adult patients with suspected sepsis,
respectively. Among identified microorganisms, the proportions of
Gram (+) and (–) bacteria were not significantly different among
adult patients, while Gram (+) bacteria were predominant among
neonatal and pediatric patients and increased over time. Geographical
differences among the proportions existed across
mainland China. Sepsis with fungus was rare but increased in
prevalence from neonatal to adult patients.
In the ecological analysis, the nationwide average mortality was
lower than 1 per 100,000 persons in mainland China during the
first decade of the 21st century. The sepsis mortality in small and
medium-sized cities and rural areas declined significantly over
time, but there was a slight increase in the mortality in major cities.
The mortality of the elderly with sepsis declined, but that of
neonates with sepsis increased dramatically, especially among
male neonates. In the epidemiological study review, the overall
positivity of the blood cultures were 17.0%, 13.3% and 10.6% among
neonatal, pediatric and adult patients with suspected sepsis,
respectively. Among identified microorganisms, the proportions of
Gram (+) and (–) bacteria were not significantly different among
adult patients, while Gram (+) bacteria were predominant among
neonatal and pediatric patients and increased over time. Geographical
differences among the proportions existed across
mainland China. Sepsis with fungus was rare but increased in
prevalence from neonatal to adult patients.
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