Diffusion-single breath (SB) study
SB gas cylinder was opened and after an automatic zero
adjustment, the actual measurement was started. The patient
should be asked to approach the mouthpiece and to close his
nose with the nose-clip. He should breathe quite normally.
After at least three breaths, the patient was asked to exhale
as deeply as possible from normal breathing. After maximal
expiration the patient was requested to inhale fast as deeply
as possible, then the patient inhaled the gas. The occlusion
time automatically started after 1/3 of inspiration. At the
end of inspiration, the patient was prevented from expiration
for the period of time set as occlusion time. The patient had
to keep the mouthpiece in his mouth and hold his breath for
10 s. The pressure curve displayed during the occlusion showed
whether the patient had held his breath or whether he had tried
to expire or inspire despite the occlusion. After the set occlusion
time had expired, the shutter was opened and the patient
was required to exhale smoothly, without hesitation or interruption
and sampling volume was exhaled via the sampling
tube. The gas sample collected for analysis remains in the tube.
The remaining air was exhaled via the opened shutter. The
sampling valve was closed and the patient could leave the
mouthpiece and thus diffusing Capacity of carbon monoxide
(DLCOSB) was measured. Informed consent was taken from
all participants. All patients shared in weight reduction program
achieved by using low caloric diet (500–1000 calories less
than recommended daily allowance, which calculated according
to The Harris–Benedict equations) for 6 months [10]. 14
(9 from group I and 5 from group II) patients could not continue
the weight reduction program and were excluded from
the study, then after weight reduction, pulmonary function
tests were repeated to all participants.
Diffusion-single breath (SB) studySB gas cylinder was opened and after an automatic zeroadjustment, the actual measurement was started. The patientshould be asked to approach the mouthpiece and to close hisnose with the nose-clip. He should breathe quite normally.After at least three breaths, the patient was asked to exhaleas deeply as possible from normal breathing. After maximalexpiration the patient was requested to inhale fast as deeplyas possible, then the patient inhaled the gas. The occlusiontime automatically started after 1/3 of inspiration. At theend of inspiration, the patient was prevented from expirationfor the period of time set as occlusion time. The patient hadto keep the mouthpiece in his mouth and hold his breath for10 s. The pressure curve displayed during the occlusion showedwhether the patient had held his breath or whether he had triedto expire or inspire despite the occlusion. After the set occlusiontime had expired, the shutter was opened and the patientwas required to exhale smoothly, without hesitation or interruptionand sampling volume was exhaled via the samplingtube. The gas sample collected for analysis remains in the tube.The remaining air was exhaled via the opened shutter. Thesampling valve was closed and the patient could leave themouthpiece and thus diffusing Capacity of carbon monoxide(DLCOSB) was measured. Informed consent was taken fromall participants. All patients shared in weight reduction programachieved by using low caloric diet (500–1000 calories less
than recommended daily allowance, which calculated according
to The Harris–Benedict equations) for 6 months [10]. 14
(9 from group I and 5 from group II) patients could not continue
the weight reduction program and were excluded from
the study, then after weight reduction, pulmonary function
tests were repeated to all participants.
การแปล กรุณารอสักครู่..
