. Representative apotome micrographs of HEM after the in vitro passive and iontophoretic administration of RhoB on the skin for 5 h from (a) iontophoretic delivery of
RhoB from SLN, (b) iontophoretic delivery of RhoB from NLC, (c) passive delivery of RhoB from SLN, and (d) passive delivery of RhoB from NLC. From the left to right and top to
bottom in each panel are the horizontal cross-section images of the skin scanned at 5mm increment in the z-axis direction from the skin surface.