Giger started with small ink drawings before progressing to oil paintings. For most of his career, Giger had worked predominantly in airbrush, creating monochromatic canvasses depicting surreal, nightmarish dreamscapes. However, he then largely abandoned large airbrush works in favor of works with pastels, markers or ink.[6]
Giger's most distinctive stylistic innovation was that of a representation of human bodies and machines in a cold, interconnected relationship, he described as "biomechanical". His main influences were painters Dado,[14] Ernst Fuchs and Salvador Dalí. He met Salvador Dalí, to whom he was introduced by painter Robert Venosa. Giger was also influenced by the work of the sculptor Stanislas Szukalski, and by the painters Austin Osman Spare and Mati Klarwein.[15] He was also a personal friend of Timothy Leary. Giger studied interior and industrial design at the School of Commercial Art in Zurich (from 1962 to 1965) and made his first paintings as a means of art therapy