Currently, the best results treating mucinous cyst-adenocarcinoma appear to be obtained with an aggressive combination of cytoreductive surgery, perioperative intraperiotneal chemohyperthermia, and early postoperative intraperitoneal chemotherapy. These measures could provide 5-year and 10-year survival rates as high as 80% and 60%, respectively. If debulking is incomplete, the survival rates are markedly reduced to only 20% and 0%, respectively, and long-term survival cannot be achieved. This tumor can be indolent in its course, and patients commonly have multiple debulking surgeries before ultimately succumbing to their disease.