The present paper describes a case study aimed at reducing the fresh water consumption and the related wastewater production in a waste-to-energy plant. The water cycle of an Italian WtE plant treating approximately 280 tMSW d1 with a specific water consumption of 1.81 m3 tMSW1 was studied. In order to obtain an efficient configuration, flow rates and pollutant concentrations of every process water flow were measured and compared with the acceptability limits (quantitative and qualitative) of each process.