Orange Juice are can prevent kidney stone disease. According to Dr. Clarita Odvina, assistant professor of internal medicine at the Charles and Jane Pak Center for Mineral Metabolism and Clinical,(2006). Found that Orange juice could potentially play an important role in the management of kidney stone disease. In the study, 13 volunteers - some with a history of kidney stones and some without - underwent three phases, each lasting one week. Chosen in random order, the phases included: a distilled water or control phase; an orange juice phase; and a lemonade phase. There was a three-week interval between phase. During each phase, volunteers drank 13 ounces of orange juice, lemonade or distilled water three times a day with meals. They also maintained a low-calcium, low-oxalate diet. Urine and blood samples were taken at intervals during each phase. researchers found, boosted the levels of citrate in the urine and reduced the crystallization of uric acid and calcium oxalate - the most frequently found ingredient in kidney stones. But lemonade did not increase the levels of citrate, an important acid neutralizer and inhibitor of kidney stone formation.