The SI values were calculated as follows: SI = IC50 normal cell/IC50 cancer cell. High SI value (>2) of a<br>compound gives a selective toxicity towards cancer cells (Badisa et al., 2009). Selectivity of the cytotoxic<br>activity of KG and EPMC compound were determined by comparing the cytotoxic activity (IC50) of KG<br>and EPMC compound against the cancerous CL-6 cell with the normal PBMC cell. Only KG showed<br>significant SI values, which is 5.36. Hence, KG display potential to be further exploited in the discovery<br>and development of new herbal medicine as a drug in cancer treatment.
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