Conclusion:
To answer the question: Yes PVCs in patients without apparent
structural heart disease are safe once we rule out risk factors.
Long QT, short QT, Brugada are easily recognized on a surface
ECG. An echocardiography will determine the LV function,
although determining which comes first PVCs or LV dysfunction
is not always easy. The Holter monitoring is mandatory to
quantify the PVC burden.
Patients without structural heart disease and with low-tomodest
PVC burdens may not require specific treatment. PVCs
at greater burdens, typically 15% to 20%, or with specific highrisk
features carry a risk of tachycardia-related cardiomyopathy
and may require treatment even if they are asymptomatic.
Treatment involves medical therapy with a beta-blocker, a
calcium channel blocker, or another antiarrhythmic drug, and
catheter ablation in selected cases.