Dithiocarbamates have attracted a great deal of importance due to their interesting chemistry and wide utility. DTCs have wide
range of uses and applications and are produced in great quantities throughout the world. The current research work was aim to
evaluate the in vitro antifungal activity of series of bis potassium dithiocarbamate derivatives. A series of bis derivatives were
synthesized by reacting the various amine derivatives of potassium dithiocarbamate with 1, 3-dichloropropanol in presence of
dimethylformamide. All the bis derivatives were characterized by IR, 1H NMR and chromatography method (TLC). The
antifungal activity was evaluated by their MIC and zone of inhibition of synthesized compounds by taking ketoconazole as
reference standard. The microbiological assay revealed that the compound NS-5 and NS-7 show promising antifungal activity