Ibuprofen is formulated as tablets caplets or capsules in
200 mg and 400 mg strengths.It is a nonsteroidal antiinflammatory
drug with a half-life of 1.8–2 h. It is one of the
safest drugs employed for treatment of inflammation, pain and
fever [1,2]. Its oral dose is 200–400 mg (5–10 mg/kg in children),
every 4–6 h to a maximum of 1.2 g per day in adults. Although it
is not the most potent of the nonsteroidal anti-inflammatory
drugs, it represents a good balance of efficacy and safety over
a wide dosage range when compared with others in the group
and it is also readily available and cost-effective.
Ibuprofen has analgesic and anti-inflammatory properties. It
is used in mild-to-moderate pain such as dysmenorrhea, headaches
(including migraine), dental pain, postoperative pain and
musculoskeletal/joint disorders including osteoarthritis, rheumatoid
arthritis and ankylosing spondylitis [3,4]. Reports have