P407 solution loaded with ALA or ALA cubosomes compared with
P407 placebo solution are shown in Fig. 6.
Results indicate that
by increasing the concentration of P407 in aqueous solutions, the
gelation temperature is lowered [24]. The influence of loading
P407 gel with ALA or ALA cubosomes on the gelation temperature
is a further lowering the CGT. The cubosomes utilized in this study
are dispersions of GMO bulk cubic phase. The cubosomes formed
are stabilized by the addition of P407, where the hydrophobic
PPO portion is presumed to adsorb to the surface of cubosomes
while the hydrophilic PEO chains extend out into the aqueous environment
to provide steric shielding