Lycorine is a natural alkaloid extracted from amaryllidaceae and it has various pharmaco- logical and microbiological effects. Researchers had revealed that lycorine can inhibit protein synthesis in eukaryotic cells (Jimenez et al., 1976) and acetylcholinesterase activity (Hoh- mann et al., 2002). In the presence of calprotectin lycorine was shown to inhibit protein synthesis and cell apoptosis in MM46 cells