GEO was dosed at 28 mg/kg/d in order to: 1) facilitate comparison with the in vivo potency of isolated gingerols, which were dosed at 25mg/kg/d, and to 2) approximate the GEO dose received by rat streated with the crude ginger extract in prior experiments (containing approximately 32mg/kg/d GEO [and 25mg/kg/d gingerols]).