Use of low GRV has not been shown to decrease the incidence of aspiration. The relation between HGRV and aspiration is, nevertheless, controversial. Mentec et al. [7] showed that the incidence of pneumonia after the onset of EN was clearly superior in patients with upper digestive intolerance to enteral feeding. On the other hand, McClave et al. [24] could not find this correlation. Other authors also found no relationship between GRV and aspiration or pneumonia [25–27].