Twelve sediments and ten water samples were collected
from different bays of Sharm el-Sheikh (~10 m deeps) on the
Red Sea coast at South Sinai, Egypt. A total of forty actinomycete
strains were isolated based on colony morphology and
microscopic appearance. The highest number of actinomycetes
were obtained from Ras Um Sid (i.e. 16 strains) followed
by Ras Mohammed (i.e. 11 strains), Sharks Bay (i.e. 9
strains) and then Um Marikha Bay (i.e. 3 strains). Several
collected water samples didn't produce actinomycetes, even
after 6 weeks of cultivation. Only three strains were isolated
from ten sea water samples. These strains were observed in
starch casein agar medium after 4 weeks. The location, direction
and the total number of actinomycetes isolated from
different samples are summarized in Table 1. The isolated
strains were cultivated in Erlenmeyer flasks each containing
100 mL of liquid Waksman medium [18]. Fermentation was carried out at 28 C for 5 days while shaking at 200 rpm.
After extraction and evaporation, different crude extracts
were produced and took a number similar to the number of
its own actinomycete strain.