In thepresentwork,mesoporousstructuredestrone(E1)imprintedFe3O4@SiO2@mSiO2 (MM-MIPs) was
preparedandappliedasextractionsorbentforselectivepre-concentrationandspecific recognitionofE1,
17β-estradiol (E2)andestriol(E3)fromwatersamples.MM-MIPspresenthigherbindingcapacity,faster
mass transferandhigherextractionefficiency forthreeestrogensthanthenon-porousstructured
Fe3O4@SiO2. ApplicationofMM-MIPstodispersivesolidphaseextractionofthreeestrogensfromspiked
tap, riverandlakewatersamplesat0.5,1.0,10 μg L1 resultedingoodrecoveriesrangingfrom85%to
95% withrelativestandarddeviationvalueslowerthan6.0%inallcases.Limitsofdetectionwereinthe
rangeof0.086–0.43 μg L1. TheextractionmethodbasedonMM-MIPsprovedtobeahighly-effective
enrichment methodwithenrichmentfactorabout1700,whichismuchhigherthanthevaluenearly620
obtained bynon-mesoporousFe3O4@SiO2, duringtheprocessofsimultaneousseparationandsensitive
determination ofestrogensincomplicatedwatersamples.Furthermore,themesoporoussilicacouldbe
expandedtoimprintothercompounds.
In thepresentwork,mesoporousstructuredestrone(E1)imprintedFe3O4@SiO2@mSiO2 (MM-MIPs) waspreparedandappliedasextractionsorbentforselectivepre-concentrationandspecific recognitionofE1,17β-estradiol (E2)andestriol(E3)fromwatersamples.MM-MIPspresenthigherbindingcapacity,fastermass transferandhigherextractionefficiency forthreeestrogensthanthenon-porousstructuredFe3O4@SiO2. ApplicationofMM-MIPstodispersivesolidphaseextractionofthreeestrogensfromspikedtap, riverandlakewatersamplesat0.5,1.0,10 μg L1 resultedingoodrecoveriesrangingfrom85%to95% withrelativestandarddeviationvalueslowerthan6.0%inallcases.Limitsofdetectionwereintherangeof0.086–0.43 μg L1. TheextractionmethodbasedonMM-MIPsprovedtobeahighly-effectiveenrichment methodwithenrichmentfactorabout1700,whichismuchhigherthanthevaluenearly620obtained bynon-mesoporousFe3O4@SiO2, duringtheprocessofsimultaneousseparationandsensitivedetermination ofestrogensincomplicatedwatersamples.Furthermore,themesoporoussilicacouldbeexpandedtoimprintothercompounds.
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