To date,numberof Bacillus subtilis natto based products are used as food or nutritional supplements with various positive impacts on human health which shows this microorganism is not only non-pathogenic but also has probiotic effects(Barbosa etal.,
2005; Tsukamoto et al.,2001). The newly developed fermented milk rich in MK-7 cansignificantly provoke immune system,bone and cardiovascular health.The changing lifest ylesand growing health awareness are the key factors that affect the market for
functional food ingredients.Given the position of heart and bone
health as a leading health issues worldwide(Brandenburg et al.,2015;Berenjianetal.,2015), product developers have the opportunity to use the outcomes of the present study to further develop a product to prevent bone and cardiovascular diseases.