Taken together, the clinical isolate identified in our
analysis provides the first evidence that RSIV infection
can cause a fatal epidemic disease in cultured marble
goby. Based on our findings, we recommended that the
fish farm owner adopt the following strategies: (1) control
the water temperature to avoid large fluctuations as far as
possible, (2) remove ill fish immediately, (3) reduce fish
stock density, (4) inspect the fry source, and (5) avoid
introducing fish from one pond into another to prevent
cross infection.