Routes of exposure during
spray vaccination
In addition to the advantage
of rapid, mass application,
vaccination by spray induces
good mucosal and systemic
immunity. When properly administered,
spray vaccination
offers multiple routes of exposure
to the vaccine, including
eye drop, nasal drop and
oral application. While in the
chicken box, droplets fall
directly on the eye and on the
nares and will be inhaled.
Droplets will also fall on the
feathers and, during preening,
will be ingested orally. Vaccine
droplets that are inhaled will
attach to the mucosae of the
upper respiratory tract while
those that are swallowed go to
the enteric tract