CRY61 is specifically induced in the luminal epithelium at the implantation site by the active blastocyst and may play a key role during embryo attachment, also CRY61 has role about vessel development in both the placenta and the embryo. Althought, CYR61 can regulate the expression of genes involved in angiogenesis and matrix remodeling, includeing vascular endothelial growth factor A (VEGF-A), VEGF-C, type I collagen, matrix metalloproteinase 1. Thus, this objective is........