In our study, net recruitment through health professionals, clinics, and health centers associated with the Motherisk program over the course of 5 years was 0.62 recruits per month. Although recruitment rate from traditional healthcare-based sources was doubled by adding new sources in Phase 2 of the study, this increase did not explain the significant increase in recruitment. Instead, the introduction of social media was strongly associated with a twelve-fold increase in recruitment rate in Phase 2. Analysis of socio-demographic characteristics between the two groups showed no differences, indicating a homogenous study population, thus alleviating concerns about selection biases based on different recruitment sources. Interrupted time-series analysis strongly endorsed the use of social media as the cause of this increase in recruitment, with a statistically significant increase in mean recruitment (p