Q: Why not remove Poison Charging and Mixed Infection and put the points on other skills for a pure PvE build?
A: Both skills are pretty useful for mass poison infection and preparing Poison Break, and Poison Charging is the key skill for mobility in Alchemists. Disease has a pretty low AoE to begin with anyway. Plus, where’s the fun if you can’t twirl around with Poison Charging or launch a Spirit Bomb like Goku onto a pile of enemies?