revealed partial regression of right pleural collection, while left
lower lobe nodule progressed into a focal nodular consolidation
(Fig. 3b). We concluded that fluconazole failed. Antifungal treatment
was changed to caspofungin (70 mg i.v. loading and 50 mg i.
v. maintenance once daily) based on the assumptions of fluconazole
unresponsive candida pneumonia or possibility of a mold
infection. On day þ26, antifungal treatment was switched to
voriconazole (400 mg i.v. twice daily loading and 200 mg i.v. twice
daily maintenance), since an oral agent would be preferable during
the prolonged treatment period.