The second alternative is the development of dentifrices
with low fluoride concentration, which are already
available in many countries. Some studies did not found
significant differences in the anticaries effectiveness
between the fluoride toothpastes with low (500-550 ppm)
and standard concentration of fluoride (1.000-1.1000
ppm) (17,18). Nevertheless, some other researches are still
controversial when considering the effectiveness of low
fluoride toothpastes (19, 20). However, several studies
assessed children older than 6 years old, which are not
in risk of dental fluorosis anymore. We cannot assume
that similar results would be seen in primary teeth as in
permanent teeth since the literature indicates that there
may be differences between primary and permanent
enamel in reactivity to cariogenic challenges (21). In
addition, the oral cavity of young children (2–6 years
old) is much smaller than that of children aged 12 or
more, so the amount of F necessary for caries preventive
effects may not be the same in these age groups. Without
the confirmation of studies that show their anticaries
effectiveness, it seems that the best balance between
the prevention of caries and dental fluorosis is obtained
with low concentrations, approximately 400-550 ppm
of fluoride, in preschool children (17, 22). The choice of
The second alternative is the development of dentifriceswith low fluoride concentration, which are alreadyavailable in many countries. Some studies did not foundsignificant differences in the anticaries effectivenessbetween the fluoride toothpastes with low (500-550 ppm)and standard concentration of fluoride (1.000-1.1000ppm) (17,18). Nevertheless, some other researches are stillcontroversial when considering the effectiveness of lowfluoride toothpastes (19, 20). However, several studiesassessed children older than 6 years old, which are notin risk of dental fluorosis anymore. We cannot assumethat similar results would be seen in primary teeth as inpermanent teeth since the literature indicates that theremay be differences between primary and permanentenamel in reactivity to cariogenic challenges (21). Inaddition, the oral cavity of young children (2–6 yearsold) is much smaller than that of children aged 12 ormore, so the amount of F necessary for caries preventiveeffects may not be the same in these age groups. Withoutthe confirmation of studies that show their anticarieseffectiveness, it seems that the best balance betweenthe prevention of caries and dental fluorosis is obtainedwith low concentrations, approximately 400-550 ppmof fluoride, in preschool children (17, 22). The choice of
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