Aqueous nanocolloids of poorly soluble materials were produced via sonicated layer-by-layer (LbL) encapsulation
with polycation / polyanion shells. Synergy of simultaneous breaking powder particles with ultrasonication and coating
them with polycations allowed for the production of 150-200 nm diameter polyelectrolyte coated nanoparticles with
sufficient surface electrical potential for colloidal stability. This technique increases water dispersibility of low soluble
materials ranging from anticancer drugs to anticorrosion agents, dyes and inorganic salts.