In addition, significant effort has been put towards the realization of immunosensors for the fast determination of this analyte in serum samples following both labeled and label-free approaches. Most of these sensors have been reviewed in recent publications (Algarra et al., 2013; Chandra et al., 2014), revealing the diversity of the methods involved for the detection of CRP but also the shift of interest to label-free methods aiming to direct and faster analysis.