Apple pomace spirits were made from dry pomace and selected yeasts strains. Two strains of indigenous cider yeasts(Saccharomyces cerevisiae and Hanseniaspora uvarum) as well as a commercial enzyme combined with a wine dry yeastwere tested. The differences between distillates were studied by means of chemical and sensory analysis. Accordingto the results of this study, treatment with enzymes with pectin methylesterase activity led to excessive levels ofdistilled methanol, and hence it use is not advisable. In contrast, the indigenous yeasts produced lower concentrationsof methanol. Moreover, using different yeast species allows the production of spirits with important differences intheir aromatic composition, which is certainly interesting from a commercial point of view. Furthermore, the resultsshowed that drying the apple pomace allows it to be preserved in good condition, thus solving the problem of theseasonality of the raw material for making apple pomace distillates.