Novel hybrid magnetic hydrogels have demonstrated their influence in several
areas, particularly in biomedical science where these innovative materials are showing
interesting applications for controlled drug delivery. A hybrid hydrogel with CoFe2O4
nanoparticles (NPs) as cross-linker agents of carboxymethylcellulose (CMC) polymer was
obtained with the aim of testing it as a system for controlled drug release. The NPs were
functionalized with (3-aminopropyl)-trimethoxysilane (APTMS) in order to introduce-NH2
groups on the surface. Infrared spectroscopy, XPS and electrochemical analysis were
performed to quantify the amino coating. The presence of magnetic nanoparticles makes
the system suitable for an application with magnetic stimulus. Preliminary studies
performed with alternating magnetic fields indicate a release of the drug-like molecules
previously loaded in the matrix.