In this nationally representative survey, we found seropositivity
to HPV 6/11/16 was significantly higher in the vaccine era
(2007–2010) compared to the pre-vaccine era (2003–2006) in
adolescent and young adult females. We also found high
agreement between seropositivity to HPV 6/11/16 and report of
HPV vaccination. Our study suggests seropositivity to HPV 6/11/16
(with or without seropositivity to HPV 18) may be a useful marker
for quadrivalent HPV vaccination coverage