Because Ewing sarcomas are rare, they are often not considered in a differential diagnosis until biopsy reveals a neoplasm known as a small round blue cell tumor. Malignancy is usually in the differential diagnosis before biopsy. For this reason, consultation with a pediatric oncologist is critical.
Ewing sarcoma should be considered in the differential diagnosis if a patient aged 10-30 years has a soft tissue or bony mass that causes the physician to consider the presence of a neoplasm.
Differential Diagnoses