Based on the clinical symptoms and radiological features, the main differential diagnosis was tuberculosis or histoplasmosis as the patient had traveled several months and years earlier in areas where these diseases were endemic. Other noninfectious hypotheses, such as lymphoma or sarcoidosis, were also suspected based on the clinical and biological features with an important alteration of the patient status associated with polyadenopathies. All of these hypotheses were then excluded by corresponding analyses.