Adult : IV Pulseless ventricular fibrillation or ventricular tachycardia 1-1.5 mg/kg, repeat if needed. Max: 3 mg/kg. In more stable patients: 50-100 mg. May repeat once or twice if needed, up to a max of 200-300 mg in 1 hr, then 1-4 mg/min via continuous infusion. Regional anaesth As 0.5% soln w/o epinephrine: 50-300 mg. Max: 4 mg/kg IM Ventricular arrhythmia emergency 300 mg, repeat after 60-90 min if needed. Parenteral Sympathetic nerve block As 1% soln: 50 mg for cervical block; 50-100 mg for lumbar block. Peripheral nerve block As 1.5% soln: Brachial plexus block: 225-300 mg. As 2% soln: Dental nerve block: 20-100 mg. As 1% soln: Intercostal nerve block: 30 mg; paracervical block: 100 mg on each side, repeated not more often than 1.5 hrly; paravertebral block: 30-50 mg; pudendal block: 100 mg on each side. As 4% soln: Retrobulbar block: 120-200 mg. Percutaneous infiltration anaesth As 0.5% or 1% soln: 5-300 mg. Epidural Epidural anaesth 2-3 mL soln for each dermatome to be anaesthesised. Lumbar epidural: 250-300 mg (as 1% soln) for analgesia and 225-300 mg (as 1.5% soln) or 200-300 mg (as 2% soln) for anaesth; thoracic epidural: 200-300 mg (as 1% soln). In obstetric caudal analgesia: 200-300 mg (as 0.5 or 1% soln). For surgical caudal anaesth: 225-300 mg (as 1.5% soln). For continuous epidural or caudal anaesth, not to repeat max doses more often than 1.5 hrly. Intraspinal Spinal anaesth Normal delivery: Up to 50 mg (as 5% hyperbaric soln) or 9-15 mg (as 1.5% hyperbaric soln). Caesarean operation: Up to 75 mg (as 5% hyperbaric soln). Other surgical procedures: 75-100 mg. Transdermal Postherpetic neuralgia As 5% patch: Apply patch once daily for up to 12 hr w/in a 24-hr period. Max: Up to 3 patches in a single application. Mouth/Throat Surface anaesth As 2% soln: For pain: 300 mg, not more often than 3 hrly. As 4% soln: Before procedures in the mouth and throat: 40-200 mg. As 10% soln: For dentistry and otorhinolaryngology procedures: Spray 10-50 mg. As 4% soln: For laryngotracheal anaesth: Spray or instill 160 mg as a single dose. Topical Surface anaesth As 5% oint: Max: 20 g in 24 hr. As 2% gel: Approx 120-220 mg into urethra several min before examination. As 4% foam: Apply 3-4 times/day. As soln: Apply 40-200 mg to affected area. As patch: Apply patch for up to 12 hr w/in a 24-hr period. Max: 1 patch/24 hr. Rectal Haemorrhoids; Painful perianal conditions Apply topically or using applicator insert rectally, up to 6 times/day. Urethral Surface anaesth As 2% gel: Female: 60-100 mg inserted into the urethra several min before examination. Male: 100-200 mg before catheterisation and 600 mg before sounding or cytoscopy. Ophth Surface anaesth Apply 2 drops; may reapply to maintain effect.