The structural properties of glycyrrhizic acid, a sweet-tasting constituent of Glycyrrhiza glabra, and its
interaction with cyclodextrins were analyzed using dynamic light scattering, isothermal titration calorimetry,
and NMR. The dynamic light scattering and NMR studies showed that glycyrrhizic acid forms
a water-soluble aggregate that disperses upon the addition of c-cyclodextrin