The use of gadolinium-based contrast agents (GBCAs) in MR imaging is well established.
GBCAs are well tolerated by a majority of patients, and their safety profile is excellent and,
by most measures, more favorable than those for iodinated contrast agents. Here we review key
aspects of MR imaging contrast agent safety and give examples from our practice. A more comprehensive article on contrast agents (39), which provides further detail on the different types of GBCAs, a detailed overview of safety-related studies, and summaries of key ACR guidelines, can be found in this monograph.